BDBM548006 4-chloro-3-(4-((S)-2-cyclohexyl-2-(1-methyl-1H-pyrazole-5-carboxamido)acetamido)-2- fluorophenyl)-2-methylpyridine 1-oxide::WO2022091056, Example 2::WO2022091056, Example 2a::WO2022091056, Example 2b

SMILES Cc1c(c(Cl)cc[n+]1[O-])-c1ccc(NC(=O)[C@@H](NC(=O)c2ccnn2C)C2CCCCC2)cc1F

InChI Key InChIKey=JFMPKWXGPUYIMX-QHCPKHFHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 548006   

TargetInterleukin-17 receptor A/(Homo sapiens (Human))
Novartis

WIPO
LigandPNGBDBM548006(4-chloro-3-(4-((S)-2-cyclohexyl-2-(1-methyl-1H-pyr...)
Affinity DataIC50:  24nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-17 receptor A/(Homo sapiens (Human))
Novartis

WIPO
LigandPNGBDBM548006(4-chloro-3-(4-((S)-2-cyclohexyl-2-(1-methyl-1H-pyr...)
Affinity DataIC50:  17nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterleukin-17 receptor A/(Homo sapiens (Human))
Novartis

WIPO
LigandPNGBDBM548006(4-chloro-3-(4-((S)-2-cyclohexyl-2-(1-methyl-1H-pyr...)
Affinity DataIC50:  49nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed