BDBM548252 (R)-2-((R)-3-methylmorpholino)-7-(trifluoromethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one::WO2022093820, Compound 18

SMILES C[C@@H]1COCCN1c1cc2C(=O)NC[C@@H](n2n1)C(F)(F)F

InChI Key InChIKey=WCVYPEQEJGHVSX-VXNVDRBHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548252   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Genentech

WIPO
LigandPNGBDBM548252((R)-2-((R)-3-methylmorpholino)-7-(trifluoromethyl)...)
Affinity DataIC50:  5.00E+4nMAssay Description: [0194] Experimental compound in DMSO was dispensed to a 384-well microplate via acoustic dispenser at 50 nl per well. At 2.5 µl per well, an enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed