BDBM548281 WO2022093820, Compound 49

SMILES C[C@@H]1COCCN1c1cc2C(=O)NC[C@@H](n2n1)C1(CC1)c1ccccc1

InChI Key InChIKey=XUMQZXNEGKZNGV-RHSMWYFYSA-N

Data  1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548281   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
GENENTECH, INC.

WIPO
LigandPNGBDBM548281(WO2022093820, Compound 49)
Show SMILES C[C@@H]1COCCN1c1cc2C(=O)NC[C@@H](n2n1)C1(CC1)c1ccccc1
Show InChI InChI=1S/C20H24N4O2/c1-14-13-26-10-9-23(14)18-11-16-19(25)21-12-17(24(16)22-18)20(7-8-20)15-5-3-2-4-6-15/h2-6,11,14,17H,7-10,12-13H2,1H3,(H,21,25)/t14-,17-/m1/s1
Affinity DataIC50: 3.50E+4nMAssay Description: [0194] Experimental compound in DMSO was dispensed to a 384-well microplate via acoustic dispenser at 50 nl per well. At 2.5 Ál per well, an enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed