BDBM548285 WO2022093820, Compound 53

SMILES COC[C@]1(CNC(=O)c2cc(nn12)N1CCOC[C@H]1C)C(C)C

InChI Key InChIKey=NSXYFTNPDHJZST-MLGOLLRUSA-N

Data  1 IC50

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548285   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
GENENTECH, INC.

WIPO
LigandPNGBDBM548285(WO2022093820, Compound 53)
Show SMILES COC[C@]1(CNC(=O)c2cc(nn12)N1CCOC[C@H]1C)C(C)C
Show InChI InChI=1S/C16H26N4O3/c1-11(2)16(10-22-4)9-17-15(21)13-7-14(18-20(13)16)19-5-6-23-8-12(19)3/h7,11-12H,5-6,8-10H2,1-4H3,(H,17,21)/t12-,16-/m1/s1
Affinity DataIC50: 3.62E+4nMAssay Description: [0194] Experimental compound in DMSO was dispensed to a 384-well microplate via acoustic dispenser at 50 nl per well. At 2.5 Ál per well, an enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed