BDBM548491 WO2022093881, Ex-9.21

SMILES Cc1cc2cnc(NC(=O)C3CC3c3ccccn3)cc2cc1N1CCN(CC1)C1(C)CCOC1

InChI Key InChIKey=HOGLVIBAZDRBME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 548491   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM548491(WO2022093881, Ex-9.21)
Affinity DataIC50:  0.0800nMAssay Description: The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed