BDBM550451 US11306098, Example 17::US11583538, Example 17

SMILES N[C@@H]1C[C@@H]2N(C1)C(COc1ccccc1)CCN([C@H](CCC(O)=O)C(=O)NCc1ccc(Cl)c(Cl)c1)C2=O

InChI Key InChIKey=HKVAKLCNSQPBMD-BMLIWITDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550451   

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM550451(US11306098, Example 17 | US11583538, Example 17)
Affinity DataIC50: <1.00E+3nMAssay Description:To evaluate the effect of compounds on TREX1 activity, test compounds were serially diluted (11-point, 3-fold) from 10 mM stock solutions and deliver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM550451(US11306098, Example 17 | US11583538, Example 17)
Affinity DataIC50: <1.00E+3nMAssay Description:For human TREX1, the nucleotide sequence of the gene construct was codon optimized for expression in the bacterial host. The sequence was incorporate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThree-prime repair exonuclease 1(Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM550451(US11306098, Example 17 | US11583538, Example 17)
Affinity DataIC50: <1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent