BDBM550462 US11306098, Example 28::US11583538, Example 45

SMILES CC(C)C[C@@H](N1CCC(CCc2ccccc2)N2C[C@H](N)C[C@H]2C1=O)C(=O)NCc1cnccn1

InChI Key InChIKey=JEVNQCASFWNXKM-PULMRVBYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550462   

TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM550462(US11306098, Example 28 | US11583538, Example 45)
Affinity DataIC50:  5.50E+3nMAssay Description:To evaluate the effect of compounds on TREX1 activity, test compounds were serially diluted (11-point, 3-fold) from 10 mM stock solutions and deliver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThree-prime repair exonuclease 1(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM550462(US11306098, Example 28 | US11583538, Example 45)
Affinity DataIC50:  5.50E+3nMAssay Description:For human TREX1, the nucleotide sequence of the gene construct was codon optimized for expression in the bacterial host. The sequence was incorporate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThree-prime repair exonuclease 1(Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM550462(US11306098, Example 28 | US11583538, Example 45)
Affinity DataIC50:  5.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent