BDBM552977 4-fluoro-N-[4-fluoro-5- (2-morpholin-4- ylpyrimidin-5-yl)-2- [(3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]-3,5- dimethylbenzamide::US11319299, Example 28
SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1cc(C)c(F)c(C)c1)-c1cnc(nc1)N1CCOCC1
InChI Key InChIKey=HZHCCOARFZTFNJ-OYRHEFFESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 552977
Affinity DataKd: 1.5nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Affinity DataIC50: 2.74E+3nMAssay Description:Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...More data for this Ligand-Target Pair