BDBM552990 N-[5-[2- (dimethylamino)pyrimidin- 5-yl]-4-fluoro-2-(4- methylpiperazin-1- yl)phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 40
SMILES CN(C)c1ncc(cn1)-c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c(cc1F)N1CCN(C)CC1
InChI Key InChIKey=ZHYKLPAWOLFHNY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 552990
Affinity DataKd: 7.80nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
Affinity DataIC50: 774nMAssay Description:Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...More data for this Ligand-Target Pair