BDBM453370 BDBM553872::US10730826, Compound 64a

SMILES COC(C)(C)C(=O)NC(CCCCN)C(=O)COc1cccnc1

InChI Key InChIKey=LLMBDOAZOZJSCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 453370   

TargetLys-gingipain(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453370(BDBM553872 | US10730826, Compound 64a)
Affinity DataIC50:  0.400nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain (Kgp) were measured in a fluorogenic assay similar t...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM453370(BDBM553872 | US10730826, Compound 64a)
Affinity DataIC50:  0.400nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent