BDBM558 N-{3-[(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl]propyl]phenyl}-5-(trifluoromethyl)pyridine-2-sulfonamide::PNU-140690::Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones::Tipranavir::U-140690

SMILES CCC[C@@]1(CCc2ccccc2)CC(=O)C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1

InChI Key InChIKey=MYXACKZCYFKMTE-JETRDCLMSA-N

Data  1 KI  1 IC50

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558   

TargetCAAX prenyl protease 1 homolog(Mus musculus)
University Of California

Curated by ChEMBL
LigandPNGBDBM558(N-{3-[(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethy...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of mouse ZMPSTE24 expressed n delta ste24 delta rce1 yeastMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed