BDBM563986 Roche-Dataset for PDE10A, Compound 300

SMILES Cc1cc(Cl)c(C)n2nc(\C=C\c3nc(nn3C)N3CCCC3)nc12

InChI Key InChIKey=OBPRDQDEZXTACT-VOTSOKGWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563986   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM563986(Roche-Dataset for PDE10A, Compound 300)
Affinity DataIC50:  0.330nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed