BDBM564109 Roche-Dataset for PDE10A, Compound 423

SMILES O=C(Nc1ccc2[nH]c(nc2c1)-c1ccccc1)c1nc(ccc1Nc1cncnc1)C1CC1

InChI Key InChIKey=SWFVAOMFSIRZTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564109   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM564109(Roche-Dataset for PDE10A, Compound 423)
Affinity DataIC50:  0.240nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed