BDBM564109 Roche-Dataset for PDE10A, Compound 423
SMILES O=C(Nc1ccc2[nH]c(nc2c1)-c1ccccc1)c1nc(ccc1Nc1cncnc1)C1CC1
InChI Key InChIKey=SWFVAOMFSIRZTR-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 564109
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche
F. Hoffmann-La Roche
Affinity DataIC50: 0.240nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair