BDBM576417 (R)-2-(1-Cyclopropyl-2-hydroxy-2-methylpropyl)-5-fluoro-7-(4-(5-methyl-1,3,4-oxadiazol- 2-yl)phenyl)isoindolin-1-one::WO2022115301, Example 3

SMILES Cc1nnc(o1)-c1ccc(cc1)-c1cc(F)cc2CN([C@H](C3CC3)C(C)(C)O)C(=O)c12

InChI Key InChIKey=AJMLNNUPHKCZGE-OAQYLSRUSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576417   

TargetCeramide glucosyltransferase(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM576417((R)-2-(1-Cyclopropyl-2-hydroxy-2-methylpropyl)-5-f...)
Affinity DataEC50:  2nMAssay Description: Using Promega’s UDP-Glo™ Glycosyltransferase assay kit (Promega Corporation, Madison, WI, USA (Promega)), GCS activity was indirectly measured by de...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed