BDBM578769 US11479550, Example 11-15(2)::US11479550, Example 11-25(2)

SMILES COCCNC(=O)c1ccc2c(C)cn([C@H](C)C(=O)Nc3cc(ccc3CCCC(O)=O)C#N)c2c1

InChI Key InChIKey=UGKFCOJBKGJTSO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 578769   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataIC50: 1.90nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataIC50: 0.570nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProstaglandin E2 receptor EP3 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM578769(US11479550, Example 11-15(2) | US11479550, Example...)
Affinity DataKi:  2.30E+3nMAssay Description:To each well of a 96 well plate, 10 μL of a medium (dimethyl sulfoxide; DMSO) which had been 10-fold diluted with an assay buffer solution (10 m...More data for this Ligand-Target Pair
In DepthDetails
US Patent