BDBM58586 2-Fluoro-benzoic acid N'-(4-hydroxy-1-methyl-2-oxo-1,2-dihydro-quinoline-3-carbonyl)-hydrazide::MLS001217552::N''-(2-fluorobenzoyl)-2-hydroxy-1-methyl-4-oxoquinoline-3-carbohydrazide::N''-(2-fluorobenzoyl)-4-hydroxy-2-keto-1-methyl-quinoline-3-carbohydrazide::N''-(2-fluorophenyl)carbonyl-1-methyl-2-oxidanyl-4-oxidanylidene-quinoline-3-carbohydrazide::N''-[(2-fluorophenyl)-oxomethyl]-2-hydroxy-1-methyl-4-oxo-3-quinolinecarbohydrazide::N'-(2-fluorobenzoyl)-2-hydroxy-4-keto-1-methyl-quinoline-3-carbohydrazide::N'-(2-fluorobenzoyl)-4-hydroxy-2-keto-1-methyl-quinoline-3-carbohydrazide::SMR000608064::cid_3115944

SMILES Cn1c2ccccc2c(O)c(C(=O)NNC(=O)c2ccccc2F)c1=O

InChI Key InChIKey=ZWHZSZXFNBURQC-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 58586   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58586(2-Fluoro-benzoic acid N'-(4-hydroxy-1-methyl-2...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM58586(2-Fluoro-benzoic acid N'-(4-hydroxy-1-methyl-2...)
Affinity DataIC50:  1.94E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetT cell receptor alpha variable 4(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM58586(2-Fluoro-benzoic acid N'-(4-hydroxy-1-methyl-2...)
Affinity DataIC50: >9.41E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCorticotropin-releasing factor-binding protein(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM58586(2-Fluoro-benzoic acid N'-(4-hydroxy-1-methyl-2...)
Affinity DataEC50:  5.36E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAlbumin(Bos taurus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM58586(2-Fluoro-benzoic acid N'-(4-hydroxy-1-methyl-2...)
Affinity DataIC50: >9.41E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM58586(2-Fluoro-benzoic acid N'-(4-hydroxy-1-methyl-2...)
Affinity DataIC50:  1.56E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay