BDBM60917 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659

SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12

InChI Key InChIKey=TVURRHSHRRELCG-UHFFFAOYSA-N

Data  20 KI  9 IC50  5 Kd  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 60917   

LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKi:  13nMAssay Description:Binding affinity against Dopamine receptor D2 in rat striatal membranes using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2018
Entry Details

TargetD(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKi:  790nMAssay Description:Compound was tested for inhibition of [3H]spiroperidol binding against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKi:  810nMAssay Description:Affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKd:  1.30E+3nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]spiroperidol from homogenized bovine pituitary Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKd:  1.90E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKd:  2.70E+3nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKd:  1.30E+4nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed