BDBM6645 4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid::CHEMBL341824::Pteridine deriv. 12

SMILES Nc1nc2ncc(CNc3ccc(cc3)C(O)=O)nc2c(=O)[nH]1

InChI Key InChIKey=JOAQINSXLLMRCV-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6645   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Banyu Tsukuba Research Institute

LigandPNGBDBM6645(4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}b...)
Affinity DataIC50:  1.60E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed