BDBM672837 (Step 1) (S)-3-(4-(7′-fluoro-2′-oxospiro [cyclopropane-1,3′-indoline]-1′-yl)phenyl)-2-(triphenylamino)methyl propionate::US20240150287, Example 14::US20240150287, Example 5
SMILES COC(=O)[C@H](Cc1ccc(cc1)N1C(=O)C2(CC2)c2cccc(F)c12)NC(c1ccccc1)(c1ccccc1)c1ccccc1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 672837
TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.
US Patent
Hangzhou Apeloa Medicine Research Institute Co.
US Patent
Affinity DataIC50: 2.87nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.
US Patent
Hangzhou Apeloa Medicine Research Institute Co.
US Patent
Affinity DataIC50: 6.21nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair