BDBM672836 (S)-3-(4-(6′-fluoro-2′-oxospiro[cyclopropane-1,3′-indoline]-1′-yl)phenyl)-2-(triphenylamino)methyl propionate::US20240150287, Example 13::US20240150287, Example 4

SMILES COC(=O)[C@H](Cc1ccc(cc1)N1C(=O)C2(CC2)c2ccc(F)cc12)NC(c1ccccc1)(c1ccccc1)c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 672836   

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672836(US20240150287, Example 4 | (S)-3-(4-(6′-fluo...)
Affinity DataIC50: 2.54nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672836(US20240150287, Example 4 | (S)-3-(4-(6′-fluo...)
Affinity DataIC50: 8.02nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent