BDBM679 BMS-186318 analog 16::[1S-[1R*,2S*(2S*,3R*)]]-[3-[[4-[4-[2-[[(Dimethylamino)-carbonyl]oxy]ethoxy]phenyl]-3-[[(1,1-dimethylethoxy)-carbonyl]amino]-2-hydroxybutyl]amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic Acid::tert-butyl N-[(2S,3R)-4-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-4-(4-{2-[(dimethylcarbamoyl)oxy]ethoxy}phenyl)-2-hydroxybutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate

SMILES CN(C)C(=O)OCCOc1ccc(C[C@H](NC(=O)OC(C)(C)C)[C@H](O)CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)cc1

InChI Key InChIKey=HGZGSIWZDXBMDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 679   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb

LigandPNGBDBM679(tert-butyl N-[(2S,3R)-4-{[(2R,3S)-3-{[(tert-butoxy...)
Affinity DataIC50: 40nMpH: 5.5 T: 2°CAssay Description:IC50 values are determined by inhibition of the cleavage of the peptidic substrate [V-S-Q-N-(beta-naphthylalanine)-P-I-V]. The IC50 value represents ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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PubMed