BDBM68211 Type II inhibitor, 5
SMILES FC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3ncnc4[nH]ccc34)cc2)c1
InChI Key InChIKey=CRNIURWEBLRATC-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 68211
TargetTyrosine-protein kinase ABL1 [1-999,Q252H](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: >5.00E+3nMpH: 7.5Assay Description:An in vitro kinase assay using phosphorylated recombinant human Abl kinase domains to phosphorylate a peptide substrate.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [1-999,Q252H](Homo sapiens (Human))
The Scripps Research Institute
The Scripps Research Institute
Affinity DataIC50: 374nMpH: 7.5Assay Description:An in vitro kinase assay using dephophorylated conformationally inactive Abl kinase was obtained by treating pure recombinant Abl with Yersinia ester...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of B-Raf (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GST-6His tagged VEGFR2 (unknown origin) using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 peptide substrate incubated for 90 mins by HTRF assa...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of TNNI3K (unknown origin)More data for this Ligand-Target Pair