BDBM75901 5-chloranyl-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one::5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)-3-pyridazinone::5-chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one::ML181::SR-02000000372::SR-02000000372-1::cid_46172919

SMILES COc1ccc(Oc2c(Cl)cnn(-c3cc(C)cc(C)c3)c2=O)cc1

InChI Key InChIKey=RTIGBOQZDVBXCO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 75901   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM75901(5-chloranyl-2-(3,5-dimethylphenyl)-4-(4-methoxyphe...)
Affinity DataIC50:  3.90E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeuropeptides B/W receptor type 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM75901(5-chloranyl-2-(3,5-dimethylphenyl)-4-(4-methoxyphe...)
Affinity DataIC50:  272nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNeuropeptides B/W receptor type 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM75901(5-chloranyl-2-(3,5-dimethylphenyl)-4-(4-methoxyphe...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity at human NPBWR1 expressed in HEK293T cells co-expressing Galphaqi3 assessed as calcium release after 15 mins by FLIPR assay assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptides B/W receptor type 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM75901(5-chloranyl-2-(3,5-dimethylphenyl)-4-(4-methoxyphe...)
Affinity DataIC50:  270nMAssay Description:Antagonist activity against human NPBWR1 expressed in HEK293 cells co-expressing Gqi3 assessed as inhibition of agonist-induced response by FLIPR ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptides B/W receptor type 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM75901(5-chloranyl-2-(3,5-dimethylphenyl)-4-(4-methoxyphe...)
Affinity DataIC50:  281nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay