BDBM8046 (4-Fluorophenyl)-[4-(2,4-dimethylthiazol-5-yl)pyrimidin-2-yl]amine::2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 17::4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(4-fluorophenyl)pyrimidin-2-amine::CS14

SMILES Cc1nc(C)c(s1)-c1ccnc(Nc2ccc(F)cc2)n1

InChI Key InChIKey=PKHXJWYQMRFPTR-UHFFFAOYSA-N

Data  2 KI  5 Kd  2 Koff  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8046   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM8046((4-Fluorophenyl)-[4-(2,4-dimethylthiazol-5-yl)pyri...)
Affinity DataKoff:  2.42E+5s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM8046((4-Fluorophenyl)-[4-(2,4-dimethylthiazol-5-yl)pyri...)
Affinity DataKon:  0.0290M-1s-1Assay Description:OctetRed_Method3More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM8046((4-Fluorophenyl)-[4-(2,4-dimethylthiazol-5-yl)pyri...)
Affinity DataKd:  121nMAssay Description:OctetRed_Method2More data for this Ligand-Target Pair
In DepthDetails PubMed