BDBM82071 CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655

SMILES COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1

InChI Key InChIKey=PNVNVHUZROJLTJ-UHFFFAOYSA-N

Data  164 KI  58 IC50  4 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82071   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Affinity DataIC50:  35nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Affinity DataIC50:  581nMAssay Description:Inhibition of norepinephrine reuptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Affinity DataIC50:  7.34E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank