BDBM8253 3-(3-chlorophenyl)-4-[(3,5-dichloro-4-hydroxyphenyl)amino]-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 6-j

SMILES Oc1c(Cl)cc(NC2=C(C(=O)NC2=O)c2cccc(Cl)c2)cc1Cl

InChI Key InChIKey=WHASIRNOCBFBSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8253   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM8253(3-(3-chlorophenyl)-4-[(3,5-dichloro-4-hydroxypheny...)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM8253(3-(3-chlorophenyl)-4-[(3,5-dichloro-4-hydroxypheny...)
Affinity DataIC50:  58nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 10 uM ATP/ [gamma-33P] ATP. Aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed