BDBM86248 CAS_364-98-7::NSC_3019::diazoxide

SMILES CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1

InChI Key InChIKey=GDLBFKVLRPITMI-UHFFFAOYSA-N

Data  2 KI  4 IC50  1 Kd  6 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86248   

LigandPNGBDBM86248(CAS_364-98-7 | NSC_3019 | diazoxide)
Affinity DataIC50:  1.94E+5nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM86248(CAS_364-98-7 | NSC_3019 | diazoxide)
Affinity DataIC50:  7.40E+5nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM86248(CAS_364-98-7 | NSC_3019 | diazoxide)
Affinity DataEC50:  3.30E+4nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed