BDBM86704 CAS_93957-54-1::Fluvastatin::cid_446155
SMILES CC(C)n1c(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)c(-c2ccc(F)cc2)c2ccccc12
InChI Key InChIKey=FJLGEFLZQAZZCD-MCBHFWOFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 86704
TargetCystic fibrosis transmembrane conductance regulator(Human)
Southern Research Institute
Curated by PubChem BioAssay
Southern Research Institute
Curated by PubChem BioAssay
Affinity DataKd: 1.10E+4nMAssay Description:Binding affinity to RXRalpha-LBD (unknown origin) measured up to 120 sec by surface plasma resonance methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant NTCP expressed in CHO cells assessed as reduction in [3H]taurocholate uptake incubated for 2 mins by scintillation co...More data for this Ligand-Target Pair
Affinity DataEC50: 7.10E+3nMAssay Description:Activation of recombinant SIRT6 (unknown origin) using fluoro substrate peptide incubated for 1 hr in presence of NAD by Fluor de Lys assay based flu...More data for this Ligand-Target Pair
Affinity DataEC50: >2.50E+5nMAssay Description:Activation of N-terminal His-tagged human SIRT6 (1 to 355 residues) expressed in Escherichia coli M15(pREP4) assessed as increase in deacetylation ac...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Agonist activity at human Nurr1 measured by Gal4-Nurr1 hybrid reporter gene assayMore data for this Ligand-Target Pair