BDBM87053 Bisanilinopyrimidine inhibitor, 7::Bisanilinopyrimidine, 3l::US9249124, 13

SMILES c1ccc(c(c1)Nc2ccnc(n2)Nc3ccc(cc3)C(=O)O)Cl

InChI Key InChIKey=BAZFHAGOCKJYHX-UHFFFAOYSA-N

Data  5 IC50  2 Kd  1 ITC

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 87053   

TargetAurora kinase A(Human)
Moffitt Cancer Center

LigandBDBM87053(Bisanilinopyrimidine, 3l | Bisanilinopyrimidine in...)Copy SMILESCopy InChI

Affinity DataIC50: 2.5nM Kd:  15nMpH: 7.4 T: 2°CAssay Description:The formation of ADP from ATP was quantified using a coupled enzyme assay (DiscoverX) in with a fluorescent resorufin dye is generated from the inter...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/18/2012
Entry Details Article
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