BDBM88560 US10189794, Compound I-2::US10618902, Compound I-2::US10774052, Compound I-2::US9695132, I-2::US9695132, I-65
SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(Nc4ccccc4NC(=O)C=C)nc3N(C)C2=O)c1Cl
InChI Key InChIKey=WILHHSWUSOIGGD-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 88560
Affinity DataIC50: <100nMpH: 7.5Assay Description:Omnia Assay Protocol for Potency Assessment Against FGFR 4 Enzyme. b) [FGFR4-WT]=2.5 nM, [ATP]=250 uM, [Y10-Sox]=10 uM (ATP KMapp 250 uM): A 10x stoc...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMpH: 7.5Assay Description:Omnia Assay Protocol for Potency Assessment Against FGFR 4 Enzyme. a) [FGFR4-WT]=10 nM, [ATP]=300 uM, [Y10-Sox]=10 uM (ATP KMapp 300 uM): A 10x stock...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:MDA-MB-453 and Huh7 cells were grown in 96-well poly-D-lysine plates (BD Bioscience, San Jose, Calif.) to 90% confluence. The cells were then incubat...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:A 10× stock solution of FGFR4-WT (PR4380C or P3054), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 10, was prepared as descr...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:A 10× stock solution of FGFR4-WT (PR4380C), (from Invitrogen, Carlsbad, Calif.) corresponding to method a in Table 7, was prepared as described below...More data for this Ligand-Target Pair