BDBM90787 1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydrochloride::GUVACINE::Guvacine hydrochloride::MLS000859975::SMR000326834::cid_11957555

SMILES OC(=O)C1=CCCNC1

InChI Key InChIKey=QTDZOWFRBNTPQR-UHFFFAOYSA-N

Data  26 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 90787   

TargetSodium- and chloride-dependent GABA transporter 1(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 90787BDBM90787(SMR000326834 | cid_11957555 | GUVACINE | MLS000859...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Rat)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 90787BDBM90787(SMR000326834 | cid_11957555 | GUVACINE | MLS000859...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 90787BDBM90787(SMR000326834 | cid_11957555 | GUVACINE | MLS000859...)
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 90787BDBM90787(SMR000326834 | cid_11957555 | GUVACINE | MLS000859...)
Affinity DataIC50: 1.87E+6nMAssay Description:Inhibition of human GABA transporter (hBGT-1) activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed