BDBM90787 1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydrochloride::GUVACINE::Guvacine hydrochloride::MLS000859975::SMR000326834::cid_11957555

SMILES OC(=O)C1=CCCNC1

InChI Key InChIKey=QTDZOWFRBNTPQR-UHFFFAOYSA-N

Data  26 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 90787   

TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM90787(1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydro...)
Affinity DataIC50:  1.15E+5nMAssay Description:Inhibition of mouse GAT3 mediated [3]GABA uptake expressed in HEK293 cells after 3 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung

Curated by ChEMBL
LigandPNGBDBM90787(1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydro...)
Affinity DataIC50:  1.10E+5nMAssay Description:Binding affinity to GAT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
Zentrum F£R Pharmaforschung

Curated by ChEMBL
LigandPNGBDBM90787(1,2,3,6-tetrahydropyridine-5-carboxylic acid;hydro...)
Affinity DataIC50:  1.19E+5nMAssay Description:Inhibitory activity against human sodium and chloride dependent GABA transporter 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed