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Found 3 Enz. Inhib. hit(s) with Target = 'Actin [R183K]'
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65515(76343-93-6 | LAT-A | LatA | Latrunculin A)
Affinity DataIC50:  110nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65506(CHEBI:80062 | Chivosazole F | SCHEMBL1889389)
Affinity DataIC50:  380nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActin [R183K](Baker's yeast)
Novartis Pharma

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)
Affinity DataIC50:  1.19E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed