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Found 1060 Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 14'
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133408(CHEMBL3632844)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133390(CHEMBL3632826)
Affinity DataKi:  0.340nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133394(CHEMBL3632830)
Affinity DataKi:  0.410nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133400(CHEMBL3632836)
Affinity DataKi:  0.420nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50155550(2,3,5,6-Tetrafluoro-N-(5-sulfamoyl-indan-2-yl)-ben...)
Affinity DataKi:  0.470nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133409(CHEMBL3632845)
Affinity DataKi:  0.670nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133389(CHEMBL3632825)
Affinity DataKi:  0.670nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133393(CHEMBL3632829)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133391(CHEMBL3632827)
Affinity DataKi:  0.75nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133397(CHEMBL3632833)
Affinity DataKi:  0.770nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133404(CHEMBL3632840)
Affinity DataKi:  0.830nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133396(CHEMBL3632832)
Affinity DataKi:  0.840nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM11625(2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiad...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50349847(CHEMBL1813208)
Affinity DataKi:  0.920nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133402(CHEMBL3632838)
Affinity DataKi:  0.930nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239274(CHEMBL4079453)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM11039(2-nonylamido-5-sulfonamidoindane | CHEMBL208532 | ...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239279(CHEMBL4070634)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50155552(4-Chloro-N-(5-sulfamoyl-indan-2-yl)-benzamide | 4-...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239274(CHEMBL4079453)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239279(CHEMBL4070634)
Affinity DataKi:  3.20nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239283(CHEMBL4068642)
Affinity DataKi:  3.20nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239281(CHEMBL4100218)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239278(CHEMBL4095957)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133405(CHEMBL3632841)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133395(CHEMBL3632831)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133407(CHEMBL3632843)
Affinity DataKi:  3.70nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50349850(CHEMBL1738787)
Affinity DataKi:  3.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133403(CHEMBL3632839)
Affinity DataKi:  4nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50185303(CHEMBL88115)
Affinity DataKi:  4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50349858(CHEMBL78755)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human CA14 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50349858(CHEMBL78755)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239271(CHEMBL4069601)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239271(CHEMBL4069601)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50386715(CHEMBL2048917)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human recombinant full length CA14-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50239271(CHEMBL4069601)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human carbonic anhydrase 14 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50185302(CHEMBL3823618)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50185295(CHEMBL3822883)
Affinity DataKi:  4.40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50185300(CHEMBL3822486)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50185299(CHEMBL3823200)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50133401(CHEMBL3632837)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human carbonic anhydrase-14 assessed as CO2 hydration activity by stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50352645(CHEMBL1822701)
Affinity DataKi:  4.90nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM11037(2-propylamido-5-sulfonamidoindane | CHEMBL205743 |...)
Affinity DataKi:  5nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50323341(CHEMBL1209039)
Affinity DataKi:  5.10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50386730(CHEMBL2048933)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human recombinant full length CA14-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50345216(2-ethyl-N-(4-sulfamoylphenyl)hexanamide | CHEMBL10...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50155554(5-Chloro-2-methoxy-N-(5-sulfamoyl-indan-2-yl)-benz...)
Affinity DataKi:  5.60nMAssay Description:Inhibition of human carbonic anhydrase 14 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  5.70nMAssay Description:Inhibition of human carbonic anhydrase-14 preincubated for 15 mins by stopped flow CO2 dehydration methodMore data for this Ligand-Target Pair
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