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2X1N:
Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design
PDB ID:
2X1N
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MMDB ID:
80073
PDB Deposition Date:
2009/12/31
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.75 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2X1N: trimeric; determined by author and by software (PISA)
Molecular Components in 2X1N
Label
Count
Molecule
Proteins (2 molecules)
C
1
Cell Division Protein Kinase 2
(Gene symbol:
CDK2
)
D
1
Cyclin-a2
(Gene symbol:
CCNA2
)
Chemicals and Non-standard biopolymers (2 molecules)
H
1
ACE-LEU-ASN-PFF-NH2
1
1
2-METHYL-N-[(1Z)-3-NITROCYCLOHEXA-2,4-DIEN-1-YLIDENE]-4,5-DIHYDRO[1,3]THIAZOLO[4,5-H]QUINAZOLIN-8-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303