2CM7: Structural Basis for Inhibition of Protein Tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics

PDB ID: 2CM7Download
MMDB ID: 40758
PDB Deposition Date: 2006/5/4
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2CM7: monomeric; determined by author and by software (PQS)
Molecular Components in 2CM7
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Phosphatase Non-receptor Type 1
(Gene symbol: PTPN1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ISOTHIAZOLIDINONE ANALOGISOTHIAZOLIDINONE ANALOG
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303