1P44: Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data

PDB ID: 1P44Download
MMDB ID: 24740
PDB Deposition Date: 2003/4/21
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 1P44: tetrameric; determined by author
Molecular Components in 1P44
Label Count Molecule
Proteins (4 molecules)
4
Enoyl-[acyl-carrier-protein] Reductase [nadh]
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
2
4
5-{[4-(9H-FLUOREN-9-YL)PIPERAZIN-1-YL]CARBONYL}-1H-INDOLE5-{[4-(9H-FLUOREN-9-YL)PIPERAZIN-1-YL]CARBONYL}-1H-INDOLE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303