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2WI5:
Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone
PDB ID:
2WI5
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MMDB ID:
75547
PDB Deposition Date:
2009/5/8
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2WI5: monomeric; determined by author and by software (PISA)
Molecular Components in 2WI5
Label
Count
Molecule
Protein (1 molecule)
A
1
Heat Shock Protein HSP 90-alpha
(Gene symbol:
HSP90AA1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303