1NL4: Crystal Structure of Rat Farnesyl Transferase in Complex With A Potent Biphenyl Inhibitor

PDB ID: 1NL4Download
MMDB ID: 22151
PDB Deposition Date: 2003/1/6
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 1NL4: dimeric; determined by author and by software (PISA)
Molecular Components in 1NL4
Label Count Molecule
Proteins (2 molecules)
1
Protein Farnesyltransferase Alpha Subunit
(Gene symbol: Fnta)
Molecule annotation
1
Protein Farnesyltransferase Beta Subunit
(Gene symbol: Fntb)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDALPHA-HYDROXYFARNESYLPHOSPHONIC ACID
3
1
4-[(3-CYANO-BENZYL)-(3-METHYL-3H-IMIDAZOL-4-YLMETHYL)-AMINO]-2-NAPHTHALEN-1-YL-BENZONITRILE4-[(3-CYANO-BENZYL)-(3-METHYL-3H-IMIDAZOL-4-YLMETHYL)-AMINO]-2-NAPHTHALEN-1-YL-BENZONITRILE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303