NCBI
National Center for
Biotechnology Information
Search
2G71:
Structure of hPNMT with inhibitor 3-fluoromethyl-7-trifluoropropyl-THIQ and AdoHcy
PDB ID:
2G71
Download
MMDB ID:
44440
PDB Deposition Date:
2006/2/27
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2G71: monomeric; determined by author and by software (PQS)
Molecular Components in 2G71
Label
Count
Molecule
Protein (1 molecule)
A
1
Phenylethanolamine N-methyltransferase
(Gene symbol:
PNMT
)
Chemicals and Non-standard biopolymers (2 molecules)
1
1
S-ADENOSYL-L-HOMOCYSTEINE
2
1
(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303