2C0O: Src family kinase Hck with bound inhibitor A-770041

PDB ID: 2C0ODownload
MMDB ID: 41355
PDB Deposition Date: 2005/9/6
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.85  Å
Source Organism:
Similar Structures:
Biological Unit for 2C0O: monomeric; determined by author and by software (PQS)
Molecular Components in 2C0O
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase HCK
(Gene symbol: HCK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-(4-{1-[4-(4-ACETYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-4-AMINO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDEN-(4-{1-[4-(4-ACETYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-4-AMINO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE
2
2
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303