2FIX: Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors

PDB ID: 2FIXDownload
MMDB ID: 37758
PDB Deposition Date: 2005/12/30
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2FIX: tetrameric; determined by author and by software (PISA)
Molecular Components in 2FIX
Label Count Molecule
Proteins (4 molecules)
4
Fructose-1,6-bisphosphatase 1
(Gene symbol: FBP1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDEN-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303