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2C6E:
Aurora A kinase activated mutant (T287D) in complex with a 5- aminopyrimidinyl quinazoline inhibitor
PDB ID:
2C6E
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MMDB ID:
37209
PDB Deposition Date:
2005/11/9
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2C6E: monomeric; determined by author and by software (PQS)
Molecular Components in 2C6E
Label
Count
Molecule
Protein (1 molecule)
A
1
Serine/threonine-protein Kinase 6
(Gene symbol:
AURKA
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{5-[(7-{[(2S)-2-HYDROXY-3-PIPERIDIN-1-YLPROPYL]OXY}-6-METHOXYQUINAZOLIN-4-YL)AMINO]PYRIMIDIN-2-YL}BENZAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303