3DM6: Beta-Secretase 1 Complexed With Statine-Based Inhibitor

PDB ID: 3DM6Download
MMDB ID: 68541
PDB Deposition Date: 2008/6/30
Updated in MMDB: 2008/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3DM6: monomeric; determined by author and by software (PISA)
Molecular Components in 3DM6
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
5-[[(2s)-2-[[(3r,4s)-5-(3,5-difluorophenoxy)-3-hydroxy-4-[[3-(methyl-methylsulfonyl-amino)-5-[[(1r)-1-phenylethyl]carbamoyl]phenyl]carbonylamino]pentanoyl ]amino]-3-methyl-butanoyl]amino]benzene-1,3-dicarboxylic Acid5-[[(2s)-2-[[(3r,4s)-5-(3,5-difluorophenoxy)-3-hydroxy-4-[[3-(methyl-methylsulfonyl-amino)-5-[[(1r)-1-phenylethyl]carbamoyl]phenyl]carbonylamino]pentanoyl ]amino]-3-methyl-butanoyl]amino]benzene-1,3-dicarboxylic Acid
2
1
Isopropyl Alcohol2-propanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303