2ZMJ: Crystal Structure of Rat Vitamin D Receptor Bound to Adamantyl Vitamin D Analogs: Structural Basis for Vitamin D Receptor Antagonism and/or Partial Agonism

PDB ID: 2ZMJDownload
MMDB ID: 66431
PDB Deposition Date: 2008/4/19
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2ZMJ: dimeric; determined by author and by software (PISA)
Molecular Components in 2ZMJ
Label Count Molecule
Proteins (2 molecules)
1
Vitamin D3 Receptor
Molecule annotation
1
Mediator of RNA Polymerase II Transcription Subunit 1
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methyl-6-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]hex-2-en-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol(1R,3R,7E,17beta)-17-{(1S,2E,5R)-5-hydroxy-1-methyl-6-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]hex-2-en-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303