2YK2: Tricyclic Series Of Hsp90 Inhibitors

PDB ID: 2YK2Download
MMDB ID: 94396
PDB Deposition Date: 2011/5/25
Updated in MMDB: 2011/11
Experimental Method:
x-ray diffraction
Resolution: 1.74  Å
Source Organism:
Similar Structures:
Biological Unit for 2YK2: monomeric; determined by author and by software (PISA)
Molecular Components in 2YK2
Label Count Molecule
Protein (1 molecule)
1
Heat Shock Protein HSP 90-alpha
(Gene symbol: HSP90AA1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
4-(5-methyl-4-phenylisoxazol-3-yl)benzene-1,3-diol4-(5-methyl-4-phenylisoxazol-3-yl)benzene-1,3-diol
2
1
1-(3h-imidazo[4,5-c]pyridin-2-yl)-3,4-dihydropyrido[2,1-a]isoindol-6(2h)-one1-(3h-imidazo[4,5-c]pyridin-2-yl)-3,4-dihydropyrido[2,1-a]isoindol-6(2h)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303