2X1N: Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design

PDB ID: 2X1NDownload
MMDB ID: 80073
PDB Deposition Date: 2009/12/31
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Similar Structures:
Biological Unit for 2X1N: trimeric; determined by author and by software (PISA)
Molecular Components in 2X1N
Label Count Molecule
Proteins (2 molecules)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
1
Cyclin-a2
(Gene symbol: CCNA2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
H
1
ACE-LEU-ASN-PFF-NH2
1
1
2-METHYL-N-[(1Z)-3-NITROCYCLOHEXA-2,4-DIEN-1-YLIDENE]-4,5-DIHYDRO[1,3]THIAZOLO[4,5-H]QUINAZOLIN-8-AMINE2-METHYL-N-[(1Z)-3-NITROCYCLOHEXA-2,4-DIEN-1-YLIDENE]-4,5-DIHYDRO[1,3]THIAZOLO[4,5-H]QUINAZOLIN-8-AMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303