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4IWC:
Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with a Dynamic Thiophene-derivative
PDB ID:
4IWC
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MMDB ID:
108709
PDB Deposition Date:
2013/1/23
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
2.24 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4IWC: tetrameric; determined by author and by software (PISA)
Molecular Components in 4IWC
Label
Count
Molecule
Proteins (4 molecules)
A
B
2
Estrogen Receptor
(Gene symbol:
ESR1
)
C
D
2
Nuclear Receptor Coactivator 2
(Gene symbol:
NCOA2
)
Chemicals and Non-standard biopolymers (2 molecules)
1
2
4,4'-thiene-2,5-diylbis(3-methylphenol)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303