4ISE: Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-(6-fluoro-4-oxoquinazolin-3(4H)-yl)-N-(1,3-thiazol-2-yl)propanamide

PDB ID: 4ISEDownload
MMDB ID: 108489
PDB Deposition Date: 2013/1/16
Updated in MMDB: 2013/04
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 4ISE: monomeric; determined by author and by software (PISA)
Molecular Components in 4ISE
Label Count Molecule
Protein (1 molecule)
1
Glucokinase
(Gene symbol: GCK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
(2S)-3-cyclohexyl-2-(6-fluoro-4-oxoquinazolin-3(4H)-yl)-N-(1,3-thiazol-2-yl)propanamide(2S)-3-cyclohexyl-2-(6-fluoro-4-oxoquinazolin-3(4H)-yl)-N-(1,3-thiazol-2-yl)propanamide
3
1
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303