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4JV9:
Co-crystal structure of MDM2 with inhibitor (2S,5R,6S)-2-benzyl-5,6-bis(4-chlorophenyl)-4-methylmorpholin-3-one
PDB ID:
4JV9
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MMDB ID:
109725
PDB Deposition Date:
2013/3/25
Updated in MMDB:
2013/06
Experimental Method:
x-ray diffraction
Resolution:
2.5 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 4JV9: monomeric; determined by author and by software (PISA)
Molecular Components in 4JV9
Label
Count
Molecule
Protein (1 molecule)
A
1
E3 Ubiquitin-protein Ligase Mdm2
(Gene symbol:
MDM2
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(2S,5R,6S)-2-benzyl-5,6-bis(4-chlorophenyl)-4-methylmorpholin-3-one
2
2
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303